Research Progress of VEGF, Adipokine and the Pathogenesis of Colorectal Cancer

Abstract

Colorectal cancer is a cancer with a high incidence of new cases and deaths in the world, and its pathogenesis needs to be further studied. Vascular endothelial cell growth factor can promote the formation of new blood vessels and play an important role in the process of tumor proliferation, invasion and migration. Adipokines include leptin, adiponectin, retinin and cytokines, and these adipokines are closely related to the occurrence and development of colorectal cancer. This paper reviews the relationship between the occurrence and development of colorectal cancer and vascular endothelial cell growth factor and adipokine as well as the relationship between vascular endothelial cell growth factor and adipokine, hoping to provide a positive theoretical basis for the prevention and treatment of colorectal cancer.