Contraception au futur
Open Access
- 1 November 2021
- journal article
- review article
- Published by EDP Sciences in médecine/sciences
- Vol. 37 (11), 1014-1020
- https://doi.org/10.1051/medsci/2021163
Abstract
L’amélioration des méthodes contraceptives et la recherche de nouvelles approches innovantes, avec un bénéfice médical ajouté, permettraient de satisfaire plus de couples, aux différentes étapes de leur vie reproductive. Les systèmes de délivrance s’améliorent, visant à une utilisation autonome et à une longue durée d’action, ce qui en facilite ainsi l’observance. Auto-injections, patchs à microaiguilles, anneaux vaginaux multipores, qui délivrent des molécules contraceptives et des molécules anti-infectieuses, promettent ainsi une double prévention, la grossesse non désirée et les maladies sexuellement transmissibles. Enfin, de nouveaux systèmes intra-utérins et de contraception permanente sont à l’étude. La recherche de nouveaux contraceptifs est une nécessité et doit se poursuivre, afin de diminuer la mortalité maternelle liée aux grossesses multiples et aux avortements, qui restent souvent à risque dans beaucoup de pays. Improving current contraceptives and discover novel methods easy to use with added health benefits would meet the needs of couples who seek alternatives to current methods. New delivery systems target user-controlled, longer-acting options to provide choice, user’s autonomy and improve compliance. Self-injections, microarray patches, pod rings able to deliver several molecules aim to prevent both pregnancies and sexually transmitted infections. Improved intrauterine systems and non-surgical permanent methods are also on the research agenda. The search for novel methods must continue, to curb maternal mortality led by multiple pregnancies and unsafe abortion, still a burden in many countries.Keywords
Funding Information
- National Institute for Child Health and Development (U54 HD29990)
This publication has 50 references indexed in Scilit:
- Chitosan/alginate multilayer film for controlled release of IDM on Cu/LDPE composite intrauterine devicesColloids and Surfaces B: Biointerfaces, 2013
- Generation of fine-scale population layers using multi-resolution satellite imagery and geospatial dataRemote Sensing of Environment, 2013
- A new combination of testosterone and nestorone transdermal gels for male hormonal contraception.Journal of Clinical Endocrinology & Metabolism, 2012
- Small-Molecule Inhibition of BRDT for Male ContraceptionCell, 2012
- Novel signaling mechanisms in the ovary during oocyte maturation and ovulationMolecular and Cellular Endocrinology, 2012
- Adjudin, a potential male contraceptive, exerts its effects locally in the seminiferous epithelium of mammalian testesReproduction, 2011
- WEE2 Is an Oocyte-Specific Meiosis Inhibitor in Rhesus Macaque Monkeys1Biology of Reproduction, 2010
- Inhibition of Human Sperm Motility by Contraceptive Anti-Eppin Antibodies from Infertile Male Monkeys: Effect on Cyclic Adenosine Monophosphate1Biology of Reproduction, 2009
- Determinants of the Rate and Extent of Spermatogenic Suppression during Hormonal Male Contraception: An Integrated AnalysisJournal of Clinical Endocrinology & Metabolism, 2008
- Attitudes toward male fertility control: results of a multinational survey on four continentsHuman Reproduction, 2005