The Role of Selenium in Controlling Reproductive Disorder in Beef Cattle
Open Access
- 30 March 2022
- journal article
- research article
- Published by Indonesian Center for Animal Research and Development (ICARD) in Indonesian Bulletin of Animal and Veterinary Sciences
- Vol. 32 (1), 37-48
- https://doi.org/10.14334/wartazoa.v32i1.2883
Abstract
Reproductive failure is regarded as a problem in the breeding of beef cattle as indicated by low calving rate, low conception rate, longer periods of calving interval, and neonatal mortality. Selenium deficiency may lead to non-infectious reproduction disorder in ruminants. The purpose of this review is to evaluate the role of selenium in preventing reproduction failure of beef cattle. In the reproduction process, selenium is required for cellular respiration, cellular oxidation, DNA and RNA replication, the integrity of cells membrane, and releasing free radicals. Selenocysteine (SeCys) is the main component of selenoprotein consisting of glutathione peroxidase (GPX) to inhibit free radicals formation and reduce risks of tissue damage. Glutathione peroxidases (GPXs) involved are: GPX-1 (cytosolic), GPX-2 (gastrointestinal specific), GPX-3 (plasma/extracellular), GPX-4 (phospholipid-hydroperoxides/intracellular) and GPX-5 (spermatozoa mitochondrial capsule). Selenium as an antioxidant is potentially involved in reducing fertility, stillbirth, abortus, and premature in cows based on oxidative stress and selenium deficiency. In male cattle, the role of selenium is to maintain the integrity of cells membrane, spermatozoa fertility, and ejaculation. The selenium deficiency may therefore affect spermatozoa fertility, motility, and fusion to oocytes due to lipid peroxidation. It is then regarded as a factor in reproductive failure mainly in the infertility of cattle. Treatments for reproductive failure due to selenium deficiency could be conducted by supplementing selenium in the mineral mix, periodical dosing of selenium salt, and providing Se-mineral block, the combination of selenium and vitamin E or selenium supplementation in soils to improve the quality of fodder and feeds.Keywords
This publication has 36 references indexed in Scilit:
- Selenoproteins: Molecular Pathways and Physiological RolesPhysiological Reviews, 2014
- Effect of trace mineral supplementation on selected minerals, energy metabolites, oxidative stress, and immune parameters and its association with uterine diseases in dairy cattleJournal of Dairy Science, 2014
- Effect of selenium on markers of risk of pre-eclampsia in UK pregnant women: a randomised, controlled pilot trialBritish Journal of Nutrition, 2014
- Evaluating micronutrient concentrations in liver samples from abortions, stillbirths, and neonatal and postnatal losses in beef calvesJournal of Veterinary Diagnostic Investigation, 2014
- Maternal‐fetal transfer of selenium in the mouseThe FASEB Journal, 2013
- Roles of antioxidant enzymes in corpus luteum rescue from reactive oxygen species-induced oxidative stressReproductive BioMedicine Online, 2012
- Selenium deficiency associations with gender, breed, serum vitamin E and creatine kinase, clinical signs and diagnoses in horses of different age groups: A retrospective examination 1996–2011Equine Veterinary Journal, 2012
- Selenium concentration of maize grain in South Africa and possible factors influencing the concentrationSouth African Journal of Animal Science, 2012
- Relationship between oxidative stress and the success of artificial insemination in dairy cows in a pasture-based systemThe Veterinary Journal, 2012
- Relationship between late embryonic mortality and the increase in plasma advanced oxidised protein products (AOPP) in dairy cowsReproduction, Fertility and Development, 2011