Calcium score as a screening method for cardiovascular disease diagnosis
Open Access
- 28 December 2019
- journal article
- Published by Silicea - Poligraf, LLC in Russian Journal of Cardiology
- No. 12,p. 153-161
- https://doi.org/10.15829/1560-4071-2019-12-153-161
Abstract
Coronary artery calcification (CAC) is characteristic of coronary atherosclerosis, which is often detected by chest computed tomography. The standardized method for assessing CAC is the calcium score (CS) using the Agatston scoring system. A semi-quantitative ECG-synchronized assessment of coronary calcium score is considered a strong prognostic factor for coronary events in asymptomatic patients. Zero CS can serve as the strongest unfavorable risk factor for cardiovascular events in 10-15 years. According to international guidelines, CS should be used in patients of intermediate and low risks with a family history of cardiovascular diseases, as well as in patients with diabetes older than 40 years. The aim of this review was to summarize current data on the clinical significance of CS taking into account the results of international multicenter studies, current international guidelines and further prospects for its wider use in cardiology practice.Keywords
This publication has 34 references indexed in Scilit:
- CT calcium scoring. History, current status and outlookDiagnostic and Interventional Imaging, 2017
- The dark and bright side of atherosclerotic calcificationAtherosclerosis, 2014
- MicroRNAs Regulate Vascular Medial CalcificationCells, 2014
- Has Our Understanding of Calcification in Human Coronary Atherosclerosis Progressed?Arteriosclerosis, Thrombosis, and Vascular Biology, 2014
- Edge dissection of calcified plaque as a possible mechanism for acute coronary syndromeJournal of Thrombosis and Thrombolysis, 2014
- miRNA‐221 and miRNA‐222 synergistically function to promote vascular calcificationCell Biochemistry and Function, 2013
- Coronary Superficial and Spotty Calcium Deposits in Culprit Coronary Lesions of Acute Coronary Syndrome as Determined by Optical Coherence TomographyThe American Journal of Cardiology, 2013
- Calcification in atherosclerosisNature Reviews Cardiology, 2009
- Coronary Calcium as a Predictor of Coronary Events in Four Racial or Ethnic GroupsThe New England Journal of Medicine, 2008
- Bone morphogenetic protein expression in human atherosclerotic lesions.JCI Insight, 1993