New Search

Export article
Open Access

Study of Some Hyndantion Derivatives as Anticonvulsant Agents

Abida, Tauquir Alam, Mohammad Asif

Abstract: Hydantoin derivatives are commonly used anticonvulsant drugs. It is generally effective against partial and tonic-clonic seizures but not in absent seizures. Phenytoin is the main drug of this group and other drugs ethotoin, mephenytoin also commonly used in the therapy of epilepsies. However, they have some adverse effects and long period of therapy to seizure control. To sort out these problems, various new hydantoin derivatives as well as prodrugs like fosphenytoin were prepared. Phenytoin is effective in some cases of trigeminal and related neuralgias. Phenytoin is also used in the treatment of cardiac arrhythmias.
Keywords: Treatment / cardiac / hydantoin / anticonvulsant / Partial / tonic / Neuralgias / Ethotoin / absent / Clonic

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

Share this article

Click here to see the statistics on "Progress in Chemical and Biochemical Research" .
Back to Top Top