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Synthesis, characterization and pharmacological activity of new 2- imino –thiazolidine-4-one derivatives

Raghdah M. Alwiswasy, Raheem Jameel M, Basim Jasim Hameed
International Journal of Research in Pharmaceutical Sciences , Volume 10, pp 1763-1769; doi:10.26452/ijrps.v10i3.1369

Abstract: A new 2-iminothiazolidin-4-ones compound and its derivatives were synthesized and characterized by FT-IR, CHN, and 1HNMR techniques. The target compounds were assessed for their anti-inflammatory and analgesic activities, and the study was performed using Swiss albino mice (25-30 g) for investigation. A hind edema model caused by , while the analgesic activity was assessed using an acetic acid-induced writhing and a hot plate test evaluated the anti-inflammatory activity.
Keywords: model / edema / Plate / hot / 1HNMR / writhing / albino / Swiss / Hind / Iminothiazolidin

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