Detection of novel coronaviruses in bats in Myanmar
Open Access
- 9 April 2020
- journal article
- research article
- Published by Public Library of Science (PLoS) in PLOS ONE
- Vol. 15 (4), e0230802
- https://doi.org/10.1371/journal.pone.0230802
Abstract
The recent emergence of bat-borne zoonotic viruses warrants vigilant surveillance in their natural hosts. Of particular concern is the family of coronaviruses, which includes the causative agents of severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and most recently, Coronavirus Disease 2019 (COVID-19), an epidemic of acute respiratory illness originating from Wuhan, China in December 2019. Viral detection, discovery, and surveillance activities were undertaken in Myanmar to identify viruses in animals at high risk contact interfaces with people. Free-ranging bats were captured, and rectal and oral swabs and guano samples collected for coronaviral screening using broadly reactive consensus conventional polymerase chain reaction. Sequences from positives were compared to known coronaviruses. Three novel alphacoronaviruses, three novel betacoronaviruses, and one known alphacoronavirus previously identified in other southeast Asian countries were detected for the first time in bats in Myanmar. Ongoing land use change remains a prominent driver of zoonotic disease emergence in Myanmar, bringing humans into ever closer contact with wildlife, and justifying continued surveillance and vigilance at broad scales.Funding Information
- United States Agency for International Development (GHN-A-OO-09-00010-00)
This publication has 52 references indexed in Scilit:
- Group C Betacoronavirus in Bat Guano Fertilizer, ThailandEmerging Infectious Diseases, 2013
- Virome Profiling of Bats from Myanmar by Metagenomic Analysis of Tissue Samples Reveals More Novel Mammalian VirusesPLOS ONE, 2013
- Discovery of Seven Novel Mammalian and Avian Coronaviruses in the Genus Deltacoronavirus Supports Bat Coronaviruses as the Gene Source of Alphacoronavirus and Betacoronavirus and Avian Coronaviruses as the Gene Source of Gammacoronavirus and DeltacoronavirusJournal of Virology, 2012
- Identification of a Severe Acute Respiratory Syndrome Coronavirus-Like Virus in a Leaf-Nosed Bat in NigeriamBio, 2010
- Recombination, Reservoirs, and the Modular Spike: Mechanisms of Coronavirus Cross-Species TransmissionJournal of Virology, 2010
- Detection and Prevalence Patterns of Group I Coronaviruses in Bats, Northern GermanyEmerging Infectious Diseases, 2008
- Global trends in emerging infectious diseasesNature, 2008
- Detection of Group 1 Coronaviruses in Bats in North AmericaEmerging Infectious Diseases, 2007
- Prevalence and Genetic Diversity of Coronaviruses in Bats from ChinaJournal of Virology, 2006
- Bats: Important Reservoir Hosts of Emerging VirusesClinical Microbiology Reviews, 2006