Angiosarcoma Metastatic to the Orbit
- 1 January 1996
- journal article
- case report
- Published by American Medical Association (AMA) in American Journal of Ophthalmology
- Vol. 114 (1), 93-96
- https://doi.org/10.1001/archopht.1996.01100130089017
Abstract
Angiosarcoma is a rare malignant endothelial cell tumor. Few reports of primary orbital angiosarcoma exist in the literature. A 46-year-old woman had a 3-month history of progressive diplopia and right-sided exophthalmos. Magnetic resonance imaging showed a right intraconal mass, consistent with a cavernous hemangioma. Ultrasound examination showed an isolated mass with moderate vascularity, consistent with a metastatic lesion. Sub-total excision through a lateral orbitotomy was performed. Tissue was stained with hematoxylineosin, periodic acid-Schiff, and immunohistochemical stains for factor VIII-related antigen and Ulex europaeus agglutinin I lectin. Lateral orbitotomy biopsy specimens showed an angiosarcoma, similar to a primary breast angiosarcoma that had been resected 2 years previously. The patient initially underwent orbital irradiation, which failed to control tumor progression. Subsequently, she underwent orbital exenteration for her only known metastasis. Despite a multidisciplinary and aggressive approach to this tumor, the tumor recurred, and the patient died.This publication has 11 references indexed in Scilit:
- Chemotherapy for Angiosarcoma of the Breast: Case Report of 30-Year Survival and Analysis of the LiteratureCancer Investigation, 1994
- Epithelioid Hemangioendothelioma of the Orbital BonesOphthalmology, 1992
- Angiosarcoma of the Breast Following Segmental Mastectomy Complicated by LymphedemaAmerican Journal of Clinical Pathology, 1987
- Angiosarcoma of skin and soft tissue: A study of forty-four casesCancer, 1981
- Immunohistochemical Identification of Factor VIII-Related Antigen in Endothelial Cells of Cutaneous Lesions of Alleged Vascular NatureAmerican Journal of Clinical Pathology, 1981
- Angiosarcoma of the maxillary sinus: Literature review and case reportHead & Neck Surgery, 1979
- Primary Orbital HemangiopericytomaAmerican Journal of Ophthalmology, 1978
- Angiosarcomas of the head and neck regionThe American Journal of Surgery, 1968
- Hemangiosarcoma of the breastCancer, 1965
- MALIGNANT ANGIOENDOTHELIOMA OF THE SKINBritish Journal of Dermatology, 1964