Clinical and phenotypical features of stroke and forecast in workers under exposure industrial noise
- 25 May 2021
- journal article
- Published by FSBI Research Institute of Occupational Health RAMS in Occupational Health and Industrial Ecology
- Vol. 61 (4), 231-237
- https://doi.org/10.31089/1026-9428-2021-61-4-231-237
Abstract
Introduction. The problem of preventing the development of stroke in workers under the influence of harmful production factors is urgent. The aim of the study was to study the characteristics of stroke in men under conditions of industrial noise exposure, to establish the prognostic value in the formation and course of the disease. Material and methods. The study involved 71 men with stroke from 30 to 65 years old, who worked in conditions of industrial noise in the professions of "pilot of civil aviation aircraft" and "adjuster of railway construction machines" for 5 years or more. In order to develop a mathematical model for predicting the development of stroke and to establish an individual risk, a group of 81 men from 30 to 65 years old, working under conditions of exposure to occupational noise for 5 years or more, who had no history of stroke data, were also examined. Using the method of sequential inclusion of the studied risk factors (Forward Stepwise), we selected those that made an independent significant contribution to the development of stroke. Based on the results obtained, a logistic regression formula was created, which determines the likelihood of stroke in men working under conditions of occupational noise. Results. In the group of patients with stroke, persons of middle age were found significantly more often - 53.5%. Ischemic stroke prevailed among clinical forms - 90.1%. Among the risk factors prevailed: arterial hypertension (AH) in 100.0% of cases, dyslipidemia factor in 78.9%, smoking factor in 59.1%. A direct moderate correlation was found between the level of systolic blood pressure, diastolic blood pressure and the index of the NIHSS 1 and NIHSS 2 scales. The influence of the following factors on the development of stroke was established: the level of total cholesterol (β-coefficient=1.0, p=0.001), the presence of atrial fibrillation factor (β-coefficient=2.9, p=0.004), the presence of a factor of alcohol abuse (β-coefficient=1.1, p=0.049), the patient has a diagnosis of grade 2 AH (β-coefficient=13, p=0.041) or a diagnosis of grade 3 hypertension (β-coefficient=1.8, p=0.008). A p(X) value exceeding 0.5 indicates a high risk of developing a stroke. The sensitivity of the proposed method was 76.1%, specificity - 74.1%. Conclusion. The proposed multivariate model is informative for the individual prediction of the development of stroke in men working in conditions of exposure to occupational noise, because reflects the degree of influence of one factor or another on the development of the disease.Keywords
This publication has 13 references indexed in Scilit:
- Occupational Noise and Hypertension Risk: A Systematic Review and Meta-AnalysisInternational Journal of Environmental Research and Public Health, 2020
- Influence of industrial noise on the development of arterial hypertension in workers of metallurgical manufacturesOccupational Health and Industrial Ecology, 2020
- Current state and main directions of preservation and strengthening of health of the working population of RussiaOccupational Health and Industrial Ecology, 2020
- Longitudinal study of occupational noise exposure and joint effects with job strain and risk for coronary heart disease and stroke in Swedish menBMJ Open, 2018
- PREVALENCE OF BLOOD CIRCULATION DISEASES AMONG WORKERS EXPOSED TO OCCUPATIONAL NOISE IN MINERAL EXTRACTION AND THEIR WORK-RELATEDNESSSiberian Scientific Medical Journal, 2018
- Reduction in stroke death rates through a package of measures to improve medical care for patients with vascular diseases in the Russian FederationProfilakticheskaya meditsina, 2018
- RISK FACTORS OF ARTERIAL HYPERTENSION IN ORGANIZED COHORT OF MALE EMPLOYEES OF THE MACHINE BUILDING PLANTRational Pharmacotherapy in Cardiology, 2017
- Lesions of cardiovascular system in the practice of a pathologistMedical almanac, 2016
- SOCIAL AND ECONOMIC GRADIENTS OF BEHAVIORAL RISK FACTORS IN RUSSIAN POPULATION (BY THE ESSE-RF STUDY)Cardiovascular Therapy and Prevention, 2015
- Effect of Exposure to Occupational Noise and Shift Working on Blood Pressure in Rubber Manufacturing Company WorkersIndustrial Health, 2012