Brenner tumors of the ovary: clinical features and outcomes in a single-center cohort
Open Access
- 8 March 2022
- journal article
- research article
- Published by Galenos Yayinevi in Journal of the Turkish-German Gynecological Association
- Vol. 23 (1), 22-27
- https://doi.org/10.4274/jtgga.galenos.2021.2021.0001
Abstract
Objective: The purpose of the present study was to evaluate the clinical and pathological features and oncological outcomes of Brenner tumors (BT). Material and Methods: Evaluation was performed on the data of 96 patients with BTs retrieved from the oncology clinic database and pathology reports between 2005 and 2020. Results: The median (range) age of the patients was 52 (22-75) years. Median (range) tumor size was 52.5 (5.0-300) mm. The tumor was benign in 37 (80.9%), borderline in one (2.2%), and malignant in the remaining eight (17.4%). Ten (21.7%) of the tumors were detected incidentally. Mixed tumor, BT plus another ovarian pathology, was found in 13 (28.2%). Recurrence developed in 2/8 (25%) with malignant BT (MBT). The stage of these patients was 3C, and both received chemotherapy after surgery. Conclusion: BTs are rare and generally detected incidentally. MBTs are treated in the same way as epithelial tumors. Due to the rarity of these tumors, lymphadenectomy and optimal chemotherapy regimens are controversial issues.Keywords
This publication has 17 references indexed in Scilit:
- A peculiar case report of extraovarian Brenner tumor arising in the omentum.World Journal of Surgical Oncology, 2017
- Malignant Brenner tumors of the ovary; a population-based analysisGynecologic Oncology, 2016
- Intensive systemic chemotherapy is effective against recurrent malignant Brenner tumor of the ovary: An analysis of 10 cases within a single centerTaiwanese Journal of Obstetrics & Gynecology, 2015
- Different staining patterns of ovarian Brenner tumor and the associated mucinous tumorAnnals of Diagnostic Pathology, 2015
- Ovarian cystic tumor composed of Brenner tumor and struma ovarii.2012
- Malignant Brenner tumor of the ovary: analysis of 13 casesInternational Journal of Clinical Oncology, 2011
- Surface Epithelial Stromal Tumors of the OvaryPublished by Elsevier BV ,2009
- Coexisting Brenner tumor and struma ovarii in the right ovary: Case report and review of the literaturePathology International, 2004
- Ovarian Brenner Tumors and Transitional Cell CarcinomaInternational Journal of Gynecological Pathology, 1993
- Synchronous multiple primary neoplasms of the upper female genital tractGynecologic Oncology, 1982