1,2,4-Triazine Chemistry Part I: Orientation of cyclization reactions of functionalized 1,2,4-triazine derivatives
Open Access
- 30 September 2010
- journal article
- Published by European Journal of Chemistry in European Journal of Chemistry
- Vol. 1 (3), 236-245
- https://doi.org/10.5155/eurjchem.1.3.236-245.54
Abstract
Orientation of heterocyclization reactions of functionalized 1,2,4-triazines were studied by effect of substituents in 1,2,4-triazine moieties, type of the solvent used in the reaction and the temperature effect. Also, it was found that cyclization process depended mainly on the chemoselective and regioselectivity states of the parent substrate as well as preferring cite of ring closure.Keywords
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