Leaders at the University of Utah Health Huntsman Cancer Institute have developed a hospital at home model for oncology patients that features ongoing monitoring and rapid response for patients with unstable, acute illness. Nurse practitioners, home health registered nurses, and other staff provide hospital-level care in the patient’s own home. Services are available within 2 hours of the patient arriving home and in response to emergent calls. Early results show reductions in hospitalizations, hospital length of stay, ED use, and cost of care.