Synthesis and crystal structure of 1,3-bis{[N,N-bis(2-hydroxyethyl)amino]methyl}-5-{[(4,6-dimethylpyridin-2-yl)amino]methyl}-2,4,6-triethylbenzene
Open Access
- 26 July 2022
- journal article
- research article
- Published by International Union of Crystallography (IUCr) in Acta Crystallographica Section E: Crystallographic Communications
- Vol. 78 (8), 825-828
- https://doi.org/10.1107/s2056989022007411
Abstract
In the crystal structure of the title compound, C30H50N4O4, the two bis(hydroxyethyl)amino moieties and the 2,4-dimethylpyridinylamino unit of the molecule are located on one side of the central benzene ring, while the ethyl substituents are oriented in the opposite direction. The dihedral angle between the planes of the aromatic rings is 73.6 (1)degrees. The conformation of the molecule is stabilized by intramolecular O-H center dot center dot center dot O (1.86-2.12 angstrom) and C-H center dot center dot center dot N (2.40, 2.54 angstrom) hydrogen bonds. Dimers of inversion-related molecules represent the basic supramolecular entities of the crystal structure. They are further connected via O-H center dot center dot center dot O hydrogen bonding into undulating layers extending parallel to the crystallographic bc plane. Interlayer interaction is accomplished by weak C-H center dot center dot center dot pi contacts.Keywords
Funding Information
- Open access funding by the Publication Fund of the Technische Universität Bergakademie Freiberg
This publication has 29 references indexed in Scilit:
- Molecular Recognition of N-Acetylneuraminic Acid by Acyclic Pyridinium- and Quinolinium-Based Receptors in Aqueous Media: Recognition through Combination of Cationic and Neutral Recognition SitesThe Journal of Organic Chemistry, 2012
- Recent developments in the molecular recognition of carbohydrates by artificial receptorsRSC Advances, 2012
- Highly Effective Recognition of Carbohydrates by Phenanthroline-Based Receptors: α- versus β-Anomer Binding PreferenceChemistry – A European Journal, 2009
- Molecular recognition of carbohydrates by acyclic receptors employing noncovalent interactionsChemical Society Reviews, 2009
- Phenanthroline Unit as a Building Block for Carbohydrate ReceptorsThe Journal of Organic Chemistry, 2008
- A short history of SHELXActa Crystallographica Section A Foundations of Crystallography, 2007
- Molecular Recognition of Carbohydrates with Acyclic Pyridine-Based ReceptorsThe Journal of Organic Chemistry, 2004
- Patterns in Hydrogen Bonding: Functionality and Graph Set Analysis in CrystalsAngewandte Chemie, 1995
- The CH/π interaction: Significance in molecular recognitionTetrahedron, 1995
- Encoding and decoding hydrogen-bond patterns of organic compoundsAccounts of Chemical Research, 1990