Phytochemical studies on traditional herbal medicines based on the ethnopharmacological information obtained by field studies
Open Access
- 13 July 2021
- journal article
- review article
- Published by Springer Science and Business Media LLC in Journal of Natural Medicines
- Vol. 75 (4), 762-783
- https://doi.org/10.1007/s11418-021-01545-7
Abstract
Traditional herbal medicines, which have been used in the matured traditional medical systems as well as those have been used in ethnic medical systems, are invaluable resources of drug seeds. Ethnobotanical and ethnopharmacological survey may provide useful information of these herbal medicines, which are valuable for searching new bioactive molecules. From this viewpoint, we have been performing the ethnobotanical and ethnopharmacological field studies in Yunnan Province and Guangxi Zhuang Autonomous Region, China, and Mongolia. Phytochemical studies on traditional herbal medicines were performed based on the information obtained by our ethnobotanical survey. Herbal medicines used in Uzbekistan and Bangladesh were also investigated on the basis of the ethnopharmacological information obtained from collaborative researchers in the respective regions. Some studies were carried out for searching active substance(s) based on bioassay-guided fractionation and isolation. Over 150 new molecules were isolated in these studies, and their various biological activities were also demonstrated. This review summarizes the results of phytochemical studies of those traditional herbal medicines as well as biological activities of the isolated molecules. Graphic abstractKeywords
This publication has 93 references indexed in Scilit:
- The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human DiseasesAdvances in Urology, 2011
- Biflavonoids from Flowers of Butea monosperma (Lam.) Taub.HETEROCYCLES, 2011
- New Flavonoid Glycosides from Elsholtzia rugulosa Hemsl.Molecules, 2009
- Spicachlorantins A and B, new dimeric sesquiterpenes from the roots of Chloranthus spicatusPhytochemistry Letters, 2009
- Biosynthesis and function of polyacetylenes and allied natural productsProgress in Lipid Research, 2008
- Four new constituents from Taraxacum mongolicumChinese Chemical Letters, 2007
- Dammarane Triterpenoids from the Roots of Gentiana rigescensJournal of Natural Products, 2007
- Species-specific SCAR markers for authentication of Sinocalycanthus chinensisJournal of Zhejiang University-SCIENCE B, 2006
- Bioactive polyacetylenes in food plants of the Apiaceae family: Occurrence, bioactivity and analysisJournal of Pharmaceutical and Biomedical Analysis, 2006
- Antipyretic Activity of Gingyo-san, a Traditional Medicine, in Influenza Virus-Infected Mice.CHEMICAL & PHARMACEUTICAL BULLETIN, 1998