Dengue fever is considered as one of the most common diseases in Vietnam, previously dengue fever rarely happened in adults, but currently it has become more common in adults and especially more dangerous for pregnant women due to its complications. Prognosis depends on the extent of disease, gestational age, placental circulatory failure during labor and bleeding after birth or after surgery. Most cases of Dengue fever in pregnancy is managed by conservative treatment, the complications are rare and include: blood clotting disorders, respiratory distress, mother-child transmission. Mortality rates is up to 10-20% when dengue haemorrhagic fever or dengue shock syndrome occurs. Prevention is the most useful in the community, however dengue fever vaccine is just in testing phase of clinical trial. One case of Dengue fever haemorrhage happened in Hung vuong hospital, Ho Chi Minh city, Vietnam reported. 26- year old woman with gestation of 37 weeks had serious Dengue fever haemorrhage. The Obstetricians and midwives followed up carefully and decided appropriate management such as platelets transfusion, vaginal delivery... saved both mother and child. Both of them discharged in the happiness of their family as well as hospital staffs after 10 days of treatment. Keywords: Dengue fever, Dengue hemorrhagic fever, Dengue Shock Syndrome, Severe thrombocytopenia