Dissolution and Bio-compatibility of ZnO Doped Bioactive Glasses after In Vitro Experiment

Abstract

This work presents the study of 60SiO2-(36-x)CaO-4P2O5-xZnO (x=1, 3, 5 mol.%) glasses synthesized by a modified sol-gel method based on a hydrothermal reaction. The thermal morphology of the glass systems was evaluated by the Thermogravimetric analysis-differential scanning calorimetry (TG-DSC) method. The in vitro assay for dissolution was evaluated by the Inductively coupled plasma-optical emission spectroscopy (ICP-OES) method. Biocompatibility testing was performed with L-929 fibroblast cells. The results show that the ZnO-doped glass systems show good bioactivity and biocompatibility.