Exercise and GLUT4
- 1 July 2020
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in Exercise and Sport Sciences Reviews
- Vol. 48 (3), 110-118
- https://doi.org/10.1249/jes.0000000000000224
Abstract
The glucose transporter GLUT4 is critical for skeletal muscle glucose uptake in response to insulin and muscle contraction/exercise. Exercise increases GLUT4 translocation to the sarcolemma and t-tubule and, over the longer term, total GLUT4 protein content. Here, we review key aspects of GLUT4 biology in relation to exercise, with a focus on exercise-induced GLUT4 translocation, postexercise metabolism and muscle insulin sensitivity, and exercise effects on GLUT4 expression.Keywords
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