Comparison of Symptoms and RNA Levels in Children and Adults With SARS-CoV-2 Infection in the Community Setting
Open Access
- 1 October 2021
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA Pediatrics
- Vol. 175 (10), e212025
- https://doi.org/10.1001/jamapediatrics.2021.2025
Abstract
The COVID-19 pandemic caused by SARS-CoV-2 has resulted in substantial morbidity and mortality worldwide. Early public health interventions, including the closure of schools, were implemented to prevent the spread of SARS-CoV-2. However, the role of children in community SARS-CoV-2 transmission remains poorly understood as most children with SARS-CoV-2 infection are asymptomatic1 or experience mild disease.2,3 There have been few community-based studies of pediatric COVID-19 cases, and thus there are limited data on the role of children in the transmission of COVID-19.4This publication has 48 references indexed in Scilit:
- Epidemiology of COVID-19 Among Children in ChinaPEDIATRICS, 2020
- Presymptomatic SARS-CoV-2 Infections and Transmission in a Skilled Nursing FacilityThe New England Journal of Medicine, 2020
- Coronavirus Disease 2019 in Children — United States, February 12–April 2, 2020Morbidity and Mortality Weekly Report (MMWR), 2020
- Virological assessment of hospitalized patients with COVID-2019Nature, 2020
- Systematic review of COVID‐19 in children shows milder cases and a better prognosis than adultsActa Paediatrica, 2020
- SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected PatientsThe New England Journal of Medicine, 2020
- The REDCap consortium: Building an international community of software platform partnersJournal of Biomedical Informatics, 2019
- Research electronic data capture (REDCap)—A metadata-driven methodology and workflow process for providing translational research informatics supportJournal of Biomedical Informatics, 2008
- The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studiesJournal of Clinical Epidemiology, 2008
- The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: Guidelines for Reporting Observational StudiesAnnals of Internal Medicine, 2007