Updates in Cerebral Venous Thrombosis
- 13 January 2022
- journal article
- review article
- Published by Springer Science and Business Media LLC in Current Cardiology Reports
- Vol. 24 (1), 43-50
- https://doi.org/10.1007/s11886-021-01622-z
Abstract
Purpose of Review Cerebral venous thrombosis (CVT) is a rare cause of stroke that most commonly affects younger women. Here, we review new literature relevant to the management and prognosis of individuals with CVT and ongoing areas of uncertainty. Recent Findings Direct-acting oral anticoagulants (DOACs) are being increasingly integrated into routine care but are not yet recommended by guidelines. Recent randomized clinical trials and available case series offer reassuring safety data. Routine use of endovascular therapy is not associated with improved outcomes. The relationship between recanalization and prognosis is uncertain. Summary The evidence base for management of CVT continues to improve. Ongoing areas of uncertainty include duration of therapy and whether certain subgroups of patients may benefit from neurointervention or personalized approaches to antithrombotic strategy. The state of knowledge will continue to benefit from large collaborative international efforts, and integration of patient partnerships to identify research priorities.Funding Information
- Michael Smith Foundation for Health Research
- Heart and Stroke Foundation of Canada
- Heart and Stroke Foundation of British Columbia and Yukon
- Vancouver Coastal Health Research Institute
This publication has 85 references indexed in Scilit:
- Apixaban for Extended Treatment of Venous ThromboembolismThe New England Journal of Medicine, 2013
- Oral Rivaroxaban for the Treatment of Symptomatic Pulmonary EmbolismThe New England Journal of Medicine, 2012
- Decompressive Surgery in Cerebrovenous ThrombosisStroke, 2011
- Treatment Variations in Cerebral Venous Thrombosis: An International SurveyCerebrovascular Diseases, 2011
- Diagnosis and Management of Cerebral Venous ThrombosisStroke, 2011
- Cerebral Venous and Sinus Thrombosis in WomenStroke, 2009
- Cerebral venous thrombosis: an updateThe Lancet Neurology, 2007
- Predictors of Outcome in Patients With Cerebral Venous Thrombosis and Intracerebral HemorrhageStroke, 2007
- Cerebral Vein and Dural Sinus Thrombosis in Elderly PatientsStroke, 2005
- Long-term Prognosis in Cerebral Venous ThrombosisStroke, 1996