Aims/ Objectives: This paper examines the dynamics of multiple slip together with thermal radiation effects on the transport of a magnetohydrodynamic Casson nanofluid passing a nonlinear porous stretchable sheet in the existence of viscous dissipation and chemical reaction.Study Design: Cross-sectional study. Methodology: The outlining equations modeling the transport phenomenon are simplified into nonlinear ordinary differential equations via the approach of similarity transformations and subsequently analyzed numerically by shooting techniques alongside Runge-Kutta Fehlberg scheme.Results: The outcomes of decisive parameters affecting the flow, heat, and nanoparticle concentration are graphically deliberated. From the investigation, it is revealed that Brownian motion, viscous dissipation, and thermophoresis parameters augment the thermal boundary layer and propel an upward growth in the temperature profile. Furthermore, the slip factor decelerates the flow and heat dissipation while the fluid movement drags in the existence of the magnetic field. Conclusion: The results obtained in this study compared favourably well with existing related studies in literature under limiting scenarios.