Post-yield and failure properties of cortical bone
- 24 August 2016
- journal article
- review article
- Published by Portico in BoneKEy Reports
- Vol. 5, 829
- https://doi.org/10.1038/bonekey.2016.60
Abstract
Ageing and associated skeletal diseases pose a significant challenge for health care systems worldwide. Age-related fractures have a serious impact on personal, social and economic wellbeing. A significant proportion of physiological loading is carried by the cortical shell. Its role in the fracture resistance and strength of whole bones in the ageing skeleton is of utmost importance. Even though a large body of knowledge has been accumulated on this topic on the macroscale, the underlying micromechanical material behaviour and the scale transition of bone's mechanical properties are yet to be uncovered. Therefore, this review aims at providing an overview of the state-of-the-art of the post-yield and failure properties of cortical bone at the extracellular matrix and the tissue level.Keywords
This publication has 124 references indexed in Scilit:
- Molecular mechanics of mineralized collagen fibrils in boneNature Communications, 2013
- Ultra-structural defects cause low bone matrix stiffness despite high mineralization in osteogenesis imperfecta miceBone, 2012
- In Vitro Fracture Testing of Submicron Diameter Collagen Fibril SpecimensBiophysical Journal, 2010
- Characterization of indentation response and stiffness reduction of bone using a continuum damage modelJournal of the Mechanical Behavior of Biomedical Materials, 2010
- Molecular and Mesoscale Mechanisms of Osteogenesis Imperfecta Disease in Collagen FibrilsBiophysical Journal, 2009
- Progressive post-yield behavior of human cortical bone in compression for middle-aged and elderly groupsJournal of Biomechanics, 2009
- Differences in the mechanical behavior of cortical bone between compression and tension when subjected to progressive loadingJournal of the Mechanical Behavior of Biomedical Materials, 2008
- Mechanical behavior of human cortical bone in cycles of advancing tensile strain for two age groupsJournal of Biomedical Materials Research Part A, 2008
- Hierarchy of bone microdamage at multiple length scalesInternational Journal of Fatigue, 2007
- The role of collagen in bone strengthOsteoporosis International, 2005