MicroRNA-7-5p Inhibits Migration, Invasion and Metastasis of Intrahepatic Cholangiocarcinoma by Inhibiting MyD88
Open Access
- 10 May 2021
- journal article
- research article
- Published by Xia & He Publishing in Journal of Clinical and Translational Hepatology
- Vol. 000 (000), 000
- https://doi.org/10.14218/jcth.2021.00021
Abstract
Intrahepatic cholangiocarcinoma (ICC) is a malignant tumor derived from intrahepatic bile duct epithelial cells. Accumulating studies report that microRNAs are widely involved in tumor migration and metastasis by regulation of target genes. miR-7-5p has been confirmed to inhibit tumor metastasis and to be related to prognosis for several malignant tumors. Our study investigated the underlying functions of miR-7-5p in ICC.Keywords
This publication has 34 references indexed in Scilit:
- Cholangiocarcinoma: Current opinion on clinical practice diagnostic and therapeutic algorithmsDigestive and Liver Disease, 2016
- Burden of Gastrointestinal, Liver, and Pancreatic Diseases in the United StatesGastroenterology, 2015
- The emergence of long non-coding RNAs in the tumorigenesis of hepatocellular carcinomaCancer Letters, 2015
- miR-7-5p suppresses cell proliferation and induces apoptosis of breast cancer cells mainly by targeting REGγCancer Letters, 2015
- Downregulation of miR-7 upregulates Cullin 5 (CUL5) to facilitate G1/S transition in human hepatocellular carcinoma cellsIUBMB Life, 2013
- PAX6, a Novel Target of microRNA-7, Promotes Cellular Proliferation and Invasion in Human Colorectal Cancer CellsDigestive Diseases and Sciences, 2013
- The Yin and Yang of Toll-like receptors in cancerOncogene, 2013
- Differential role of MyD88 and Mal/TIRAP in TLR2-mediated gastric tumourigenesisOncogene, 2013
- Myeloid Differentiation Factor 88 Promotes Growth and Metastasis of Human Hepatocellular CarcinomaClinical Cancer Research, 2013
- MyD88 and its divergent toll in carcinogenesisTrends in Immunology, 2013