A Review of Different Analytical Techniques for Fexofenadine Hydrochloride and Montelukast Sodium in Different Matrices
- 3 January 2020
- journal article
- review article
- Published by Taylor & Francis Ltd in Critical Reviews in Analytical Chemistry
- Vol. 51 (3), 232-245
- https://doi.org/10.1080/10408347.2019.1709410
Abstract
Fexofenadine hydrochloride is an antihistamine agent used for the treatment of allergic disorders like rhinitis. It is a second generation antihistamine. Montelukast sodium is an anti-asthmatic agent and leukotriene receptor antagonist used in the treatment of respiratory disorders. This article exemplifies the reported analytical methods like electrometric methods, ultraviolet spectroscopy, mass spectroscopy, thin layer chromatography, high performance liquid chromatography, high performance thin layer chromatography and tandem spectroscopy for determination of fexofenadine HCl and montelukast sodium in dosage form and in biological matrices. This review covers almost all the analytical methods for fexofenadine hydrochloride and montelukast sodium form 1968-2018 years. Complete analytical validation parameters reported are discussed in this review for both analytes. Among various analytical methods, HPLC and UV-visible spectrophotometry were found to be the most extensively used methods by the researchers.Keywords
Funding Information
- C. L. Baid Metha College of Pharmacy
This publication has 53 references indexed in Scilit:
- Development and validation of RP-HPLC method for simultaneous estimation of Montelukast Sodium and Fexofenadine hydrochloride in combined dosage formJournal of Pharmacy Research, 2013
- Stability-indicating HPLC method for simultaneous determination of montelukast and fexofenadine hydrochlorideIndian Journal of Pharmaceutical Sciences, 2013
- Method Development and Validation for the Simultaneous Determination of Fexofenadine Hydrochloride and Montelukast Sodium in Drug Formulation Using Normal Phase High-Performance Thin-Layer ChromatographyInternational Scholarly Research Notices, 2012
- Identification and Characterization of an Oxidative Degradation Product of Fexofenadine, Development and Validation of a Stability Indicating RP-UPLC Method for the Estimation of Process Related Impurities and Degradation Products of Fexofenadine in Pharmaceutical FormulationsScientia Pharmaceutica, 2012
- Development of validated stability-indicating chromatographic method for the determination of fexofenadine hydrochloride and its related impurities in pharmaceutical tabletsChemistry Central Journal, 2011
- Validation and application of a liquid chromatography–tandem mass spectrometric method for quantification of the drug transport probe fexofenadine in human plasma using 96-well filter platesJournal of Chromatography B, 2010
- Development and validation of a RP-HPLC method for estimation of montelukast sodium in bulk and in tablet dosage formIndian Journal of Pharmaceutical Sciences, 2010
- Method Development and Validation of Montelukast in Human Plasma by HPLC Coupled with ESI-MS/MS: Application to a Bioequivalence StudyScientia Pharmaceutica, 2010
- Liquid chromatographic determination of fexofenadine in human plasma with fluorescence detectionJournal of Pharmaceutical and Biomedical Analysis, 2004
- Determination of montelukast (MK-0476) and its S-enantiomer in human plasma by stereoselective high-performance liquid chromatography with column-switchingJournal of Pharmaceutical and Biomedical Analysis, 1997