The article presents the results of mapping the biotopes of the “Kreidova Flora” Nature Reserve, which is one of the key areas of the eco-network of the local level of the newly created Kramatorsk district. This district includes almost entirely “Sviati Hory” National Nature Park, an object of the Nature Reserve Fund of Ukraine (NRF) with the highest amount of estimated points for a comprehensive assessment of sozological value, which belongs to a group of the first class. Two NRF objects (including the “Kreidova Flora” Nature Reserve) were from the group of the second class: one from the group of the third: nine from the group of the fifth class: and one from a group of the sixth class. The total number of points of the studied NRF objects of the newly created district is 465, which is a significant indicator. The key areas of the local level eco-network are the NRF with adjacent natural areas, which together form clusters. The ecological corridors of the local level are the river network of the district and the network of forest belts. As buffer zones for river-type eco-corridors, it is proposed to consider a minimum 200-meter water protection zone in accordance with Art. 87 of the Water Code of Ukraine. Restoration areas of the local econetwork of Kramatorsk district should be all areas with disturbed natural landscape (abandoned quarries, heaps), as well as abandoned agricultural lands, where it is proposed to introduce revalidation measures. The obtained maps and databases of distribution of different types of biotopes on the territory of the reserve will be the basis for its management plan, and this technique can be used within other structural elements of ecological networks. According to the same principle, it is considered necessary to conduct research in the entire study area, as well as other areas of Donetsk region.