Langerhans cell histiocytosis revisited: Case report with review
Open Access
- 1 January 2015
- journal article
- Published by Medknow in Contemporary Clinical Dentistry
- Vol. 6 (3), 432-436
- https://doi.org/10.4103/0976-237x.161912
Abstract
Langerhans cell histiocytosis (LCH) is a group of idiopathic disorders characterized by proliferation of bone marrow derived Langerhans cells and mature eosinophils. Their clinical features simulate common oral findings such as gingival enlargement, oral ulcers, and mobility of teeth, along with nonspecific radiographic features; hence, diagnosing such lesions becomes difficult for the oral physicians. These lesions are commonly seen in childhood; however, we are reporting a case of LCH in 29-year-old adult male. A provisional diagnosis of giant cell granuloma was considered based on history and examination, although the lesion was histologically proven to be LCH and was confirmed with immunohistochemical staining of S100 protein and CD1a antigen. The purpose of this paper is to enhance the understanding of diverse, nonpathognomical oral presentation of LCH that is easily misdiagnosed and overlooked by dentist.Keywords
This publication has 11 references indexed in Scilit:
- A rare occurrence of Langerhans cell histiocytosis in an adultJournal of Oral and Maxillofacial Pathology, 2014
- Oral manifestion of Langerhans cell histiocytosis mimicking inflammationIndian Journal of Dental Research, 2014
- Langerhans Cell Histiocytosis: An Illusion of HopeInternational Journal of Clinical Pediatric Dentistry, 2013
- Langerhans’s cell histiocytosis in old subjects: two rare case reports and review of the literatureGerodontology, 2012
- Langerhans cell histiocytosis with oral manifestations: a rare and unusual case reportJournal of Clinical and Experimental Dentistry, 2012
- Langerhans cell histiocytosisJournal of Indian Society of Periodontology, 2011
- Langerhans Cell Histiocytosis of Maxilla and Mandible in 6 Years Old Child: A Case ReportInternational Journal of Clinical Pediatric Dentistry, 2009
- Langerhans cell histiocytosis: literature review and descriptive analysis of oral manifestations.2009
- Treatment of Langerhans cell histiocytosis--evolution and current approaches.1994
- Results of Treatment of 127 Patients with Systemic Histiocytosis (Letterer-Siwe Syndrome, Schuller-Christian Syndrome and Multifocal Eosinophilic Granuloma)Medicine, 1981