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A Short Commentary Based on our Article Entitled “Capillary Networks for Bio-Artificial Three-Dimensional Tissues Fabricated Using Cell Sheet Based Tissue Engineering”


Abstract: The development of organ-like tissues is the next major challenge facing regenerative medicine. Organ-like structures have been synthesized on a small scale, but overcoming current problems with cell sourcing and scalability will facilitate the creation of cardiac assist devices and organs for transplantation. A major obstacle to generating Three-Dimensional (3D) tissues is that diffusion is inadequate for the supply of oxygen/nutrients and removal of waste products, which limits the thickness of the structure to about 0.1 mm
Keywords: structures / Organ like / tissues / Dimensional / cardiac assist / next major / waste products / Based Tissue / regenerative medicine

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