Alteration in cerebrospinal fluid (CSF) markers associated with α-synucleinopathies

Abstract
Rapid eye movement sleep behavior disorder (RBD) is linked to other α-synucleinopathies such as Parkinson’s disease and Lewy body dementia. It is essential to consider and exclude RBD while studying CSF markers in the latter two to avoid confounding bias and improve test results’ specificity.