. The development of modern medical information systems (MIS) should be based not only on the number of possible actions, records and protection of the patient’s personal data, but also on the automated improvement of medical care for the population. Today, having a huge digital potential with the beginning of electronic medical records, we do not use it at all in matters of accounting, research and control of adjustable risk factors for non-communicable diseases. The article describes the development of a registration model and further analysis of adjustable risk factors using modern medical information systems without significant expenditures (time and money) for their improvement. MIS is a software and hardware complex that prepares and supports the processes of collecting, storing and processing of information in medicine and health care. The proposed changes in the MIS requires the the fixation of the following indicators – arterial hypertension, smoking, overweight, dyslipidemia, elevated blood glucose, sedentary lifestyle. The fundamental condition for the operation of MIS is the maximum simplification of the procedure for medical workers, the elimination of ineffective processes of manual processing and analysis of medical data and the provision of effective information exchange with other information systems. The frequency with which the system proposes to update the specified data, the inability to close the visit without entering information, should be individual for each patient, including age, levels and values of previously entered data. One of the main tasks of MIS, solved in clinical institutions, is the further analysis of the data, the organization of the processing of this information. The introduction of a dynamic observation system with the identification of risk factors will make possible to analyze changes in the level of individual risk for each patient, assess the health of a society, a region, or draw conclusions on a national scale.