Letalidade hospitalar por COVID-19 em quatro capitais brasileiras e sua possível relação temporal com a variante Gama, 2020-2021
Open Access
- 1 January 2021
- journal article
- research article
- Published by FapUNIFESP (SciELO) in Epidemiologia e Serviços de Saúde
- Vol. 30 (4), e2021709
- https://doi.org/10.1590/s1679-49742021000400024
Abstract
Objective: To describe in-hospital and intensive care unit (ICU) case fatality rates due to COVID-19 in four Brazilian state capitals, during the months of epidemic peaks and previous months. Methods: This was an ecological study using monthly data from the Influenza Epidemiological Surveillance Information System, between 2020-2021, in individuals aged 20 years or older. Case fatality rate and mortality were estimated with 95% confidence intervals. Results: In Manaus, the capital city of the state of Amazonas, ICU case fatality rate among those >59 years old was lower in December/2020 (80.9% –95%CI 78.4;83.3) and during the peak in January/2021 (79.9% –95%CI 77.4;82.5), compared to the peak in April/2020 (88.2% –95%CI 86.1;90.3). In São Paulo, the capital city of the state of São Paulo, Curitiba, the capital city of the state of Paraná, and Porto Alegre, the capital city of the state of Rio Grande do Sul, there was a decrease or stability in ICU and in-hospital case fatality rate in January/2021, compared to the reference month in 2020. Conclusion: In January/2021, in-hospital and ICU case fatality rates decreased or remained stable in the four state capitals, especially in Manaus, and during the epidemic peak with the prevalence of the Gamma variant.Keywords
This publication has 21 references indexed in Scilit:
- Hospital load and increased COVID-19 related mortality in IsraelNature Communications, 2021
- Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in EnglandNature, 2021
- Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7Nature, 2021
- In-hospital mortality from severe COVID-19 in a tertiary care center in Mexico City; causes of death, risk factors and the impact of hospital saturationPLOS ONE, 2021
- Characterisation of the first 250 000 hospital admissions for COVID-19 in Brazil: a retrospective analysis of nationwide dataThe Lancet Respiratory Medicine, 2021
- Estimating the real burden of disease under a pandemic situation: The SARS-CoV2 casePLOS ONE, 2020
- A country level analysis measuring the impact of government actions, country preparedness and socioeconomic factors on COVID-19 mortality and related health outcomesEClinicalMedicine, 2020
- Ethnic and regional variations in hospital mortality from COVID-19 in Brazil: a cross-sectional observational studyThe Lancet. Global Health, 2020
- Health system collapse 45 days after the detection of COVID-19 in Ceará, Northeast Brazil: a preliminary analysisRevista da Sociedade Brasileira de Medicina Tropical, 2020
- Analysis of COVID-19 under-reporting in BrazilRevista Brasileira de Terapia Intensiva, 2020