Dysregulated Expression and Subcellular Localization of Base Excision Repair (BER) Pathway Enzymes in Gallbladder Cancer
Open Access
- 1 March 2018
- journal article
- research article
- Vol. 7 (2), 119-132
- https://doi.org/10.22088/IJMCM.BUMS.7.2.119
Abstract
Base excision repair (BER) pathway is one of the repair systems that have an impact on the radiotherapy and chemotherapy for the cancer patients. The molecular pathogenesis of gallbladder cancer is not known extensively. In the present study we investigated whether the expression of AP endonuclease 1 (APE1) and DNA polymerase ...This publication has 29 references indexed in Scilit:
- Subcellular localization of apurinic endonuclease 1 promotes lung tumor aggressiveness via NF-κB activationOncogene, 2010
- Human apurinic/apyrimidinic endonuclease (APE1) is a prognostic factor in ovarian, gastro-oesophageal and pancreatico-biliary cancersBritish Journal of Cancer, 2010
- Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapyOncogene, 2009
- Gastrointestinal Hyperplasia with Altered Expression of DNA Polymerase βPLOS ONE, 2009
- Expression of Apurinic/Apyrimidinic Endonuclease‐1 (APE‐1) in H. pylori‐Associated Gastritis, Gastric Adenoma, and Gastric CancerHelicobacter, 2008
- DNA Repair Pathway Profiling and Microsatellite Instability in Colorectal CancerClinical Cancer Research, 2006
- Difference in expression level and localization of DNA polymerase beta among human esophageal cancer focus, adjacent and corresponding normal tissuesDiseases of the Esophagus, 2006
- Defective DNA Strand Break Repair after DNA Damage in Prostate Cancer CellsCancer Research, 2004
- Epidemiology and Molecular Pathology of Gallbladder CancerCA: A Cancer Journal for Clinicians, 2001
- Enhanced expression and activity of DNA polymerase β in human ovarian tumor cells: impact on sensitivity towards antitumor agentsOncogene, 2001