New Search

Export article
Open Access

What Causes Waldenström's Macroglobulinemia: Genetic or Immune-Related Factors, or a Combination?

, Ola Landgren
Published: 1 February 2011
Clinical Lymphoma Myeloma and Leukemia , Volume 11, pp 85-87; doi:10.3816/clml.2011.n.015

Abstract: Population-based studies suggest a role for chronic immune stimulation and genetic factors in the causation of lymphoplasmacytic lymphoma (LPL)/Waldenström’s macroglobulinemia (WM). In this review we summarize and discuss our current understanding on etiology and pathogenesis of LPL/WM. We also highlight on gaps in the literature and propose future directions for population-based and molecular studies designed to expand our knowledge and uncover biological underpinnings of identified associations. Further, we address clinical implications and provide perspective on the relevance of these data for patient counseling and clinical follow-up.
Keywords: Stimulation / Etiology / causation / lymphoplasmacytic / Macroglobulinemia / Expand / Lpl/wm / Waldenstrm's

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

Share this article

Click here to see the statistics on "Clinical Lymphoma Myeloma and Leukemia" .
References (22)
    Cited by 7 articles
      Back to Top Top