Post-infectious neurological disorders
Open Access
- 1 January 2020
- journal article
- review article
- Published by SAGE Publications in Therapeutic Advances in Neurological Disorders
Abstract
A multitude of environmental factors can result in breakdown of immune tolerance in susceptible hosts. Infectious pathogens are among the most important environmental triggers in the pathogenesis of autoimmunity. Certain autoimmune disorders have a strong association with specific infections. Several neurological autoimmune disorders are thought to occur through post-infectious mechanisms. In this review, we discuss the proposed mechanisms underlying pathogen-induced autoimmunity, and highlight the clinical presentation and treatment of several post-infectious autoimmune neurological disorders. We also highlight post-infectious neurological disorders in the setting of recent outbreaks.Keywords
This publication has 169 references indexed in Scilit:
- Intravenous immunoglobulin for Guillain-Barré syndromePublished by Wiley ,2012
- Neuromuscular Manifestations of West Nile Virus InfectionFrontiers in Neurology, 2012
- Narcolepsy onset is seasonal and increased following the 2009 H1N1 pandemic in chinaAnnals of Neurology, 2011
- Clinical significance of glutamic acid decarboxylase antibodies in patients with epilepsyEpilepsia, 2010
- Elevated Tribbles homolog 2–specific antibody levels in narcolepsy patientsJCI Insight, 2010
- Infections and autoimmunity – friends or foes?Trends in Immunology, 2009
- Narcolepsy is strongly associated with the T-cell receptor alpha locusNature Genetics, 2009
- Infections and vaccinations preceding childhood Guillain-Barré syndrome: a prospective studyEuropean Journal of Pediatrics, 2006
- Acute Disseminated EncephalomyelitisArchives of Neurology, 2005
- West Nile Virus–associated Flaccid ParalysisEmerging Infectious Diseases, 2005