Microwave ablation for lung cancer patients with a single lung: Clinical evaluation of 11 cases
Open Access
- 12 March 2018
- journal article
- research article
- Published by Wiley in Thoracic Cancer
- Vol. 9 (5), 548-554
- https://doi.org/10.1111/1759-7714.12611
Abstract
Background The study was conducted to retrospectively evaluate the safety and effectiveness of computed tomography (CT)-guided percutaneous microwave ablation (MWA) for peripheral non-small cell lung cancer (NSCLC) in 11 patients with a single lung after pneumonectomy. Methods From May 2011 to March 2015, 11 single-lung patients (8 men and 3 women; mean age 60.3 years, range 46–71) with peripheral NSCLC underwent 12 sessions of MWA. Eleven tumors measuring 13–52 mm (mean 30.2 mm) were treated. Follow-up was performed via CT scan at 1, 3, 6, 12, 18, and 24 months after the procedure and annually thereafter. Clinical outcomes were evaluated and complications after MWA were summarized. Results At a median follow-up period of 20 months (range 6–38), four patients showed evidence of local recurrence at a rate of 36.4% (4/11). Median overall survival was 20 months. The overall survival rates at one, two, and three years after MWA were 88.7%, 63.6%, and 42.3%, respectively. Complications after MWA included pneumothorax (33.3%), hemoptysis (33.3%), intrapulmonary bleeding (25%), pleural effusion (16.7%), and pulmonary infection (8.3%). None of the patients died during the procedure or in the 30 days after MWA. Conclusion CT-guided percutaneous MWA is safe and effective for the treatment of peripheral NSCLC in patients with a single lung after prior pneumonectomy.Keywords
This publication has 32 references indexed in Scilit:
- Patients’ survival in lung malignancies treated by microwave ablation: our experience on 56 patientsEuropean Journal of Radiology, 2012
- Complications of microwave and radiofrequency lung ablation: personal experience and review of the literatureLa radiologia medica, 2011
- Radiofrequency, microwave and laser ablation of pulmonary neoplasms: Clinical studies and technical considerations—Review articleEuropean Journal of Radiology, 2011
- Pulmonary Radiofrequency Ablation in Patients with a Single Lung: Feasibility, Efficacy, and ToleranceRadiology, 2011
- A Systematic Review of Radiofrequency Ablation for Lung TumorsAnnals of Surgical Oncology, 2008
- Risk factors for local progression after percutaneous radiofrequency ablation of lung tumorsCancer, 2006
- Pulmonary radiofrequency ablation in a single lung patientThorax, 2006
- The Efficacy of Preemptive Analgesia for Acute Postoperative Pain Management: A Meta-AnalysisAnesthesia & Analgesia, 2005
- Lung resection for bronchogenic carcinoma after pneumonectomy: a safe and worthwhile procedureEuropean Journal of Cardio-Thoracic Surgery, 2004
- Percutaneous Radiofrequency Ablation of Malignancies in the LungAmerican Journal of Roentgenology, 2000