Cognitive and behavioral manifestations in SARS-CoV-2 infection: not specific or distinctive features?
- 12 April 2021
- journal article
- review article
- Published by Springer Science and Business Media LLC in Neurological Sciences
- Vol. 42 (6), 2273-2281
- https://doi.org/10.1007/s10072-021-05231-0
Abstract
Patients with COVID-19 are increasingly reported to suffer from a wide range of neurological complications, affecting both the central and peripheral nervous system. Among central manifestations, cognitive and behavioral symptoms are to date not exhaustively detailed. Furthermore, it is not clear whether these represent a combination of non-specific complications of a severe systemic disease, not differing from those usually seen in patients suffering from heterogenous pathological conditions affecting the central nervous system, or instead, they are a peculiar expression of COVID-19 neurotropism; in other words, if the infection has a coincidental or causal role in such patients. We examined both hypotheses, reporting opposite points of view, with the aim to stimulate discussion and raise awareness of the topic.Keywords
This publication has 78 references indexed in Scilit:
- The Other Side of CAR T-Cell Therapy: Cytokine Release Syndrome, Neurologic Toxicity, and Financial BurdenAsco Educational Book, 2019
- Neurological toxicities associated with chimeric antigen receptor T-cell therapyBrain, 2019
- ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector CellsTransplantation and Cellular Therapy, 2018
- Clinical and Biological Correlates of Neurotoxicity Associated with CAR T-cell Therapy in Patients with B-cell Acute Lymphoblastic LeukemiaCancer Discovery, 2018
- The Association between Acute Respiratory Distress Syndrome, Delirium, and In-Hospital Mortality in Intensive Care Unit PatientsAmerican Journal of Respiratory and Critical Care Medicine, 2015
- Long-Term Cognitive Impairment after Critical IllnessThe New England Journal of Medicine, 2013
- The cerebral effects of ascent to high altitudesThe Lancet Neurology, 2009
- Neurological problems on the ICUClinical Medicine, 2007
- Identification of Viruses in Patients With Postviral Olfactory DysfunctionThe Laryngoscope, 2007
- Quality of life, emotional, and cognitive function following acute respiratory distress syndromeJournal of the International Neuropsychological Society, 2004