Reduced brain cell proliferation following somatic injury is buffered by social interaction in electric fish, Apteronotus leptorhynchus
- 25 May 2020
- journal article
- research article
- Published by Wiley in Developmental Neurobiology
- Vol. 80 (5-6), 168-177
- https://doi.org/10.1002/dneu.22760
Abstract
In many species, the negative effects of aversive stimuli are mitigated by social interactions, a phenomenon termed social buffering. In one form of social buffering, social interactions reduce the inhibition of brain cell proliferation during stress. Indirect predator stimuli (e.g. olfactory or visual cues) are known to decrease brain cell proliferation, but little is known about how somatic injury, as might occur from direct predator encounter, affects brain cell proliferation and whether this response is influenced by conspecific interactions. Here, we assessed social buffering of brain cell proliferation in an electric fish, Apteronotus leptorhynchus , by examining the separate and combined effects of tail injury and social interactions. We mimicked a predator‐induced injury by amputating the caudal tail tip, exposed fish to paired interactions that varied in timing, duration and recovery period, and measured brain cell proliferation and the degree of social affiliation. Paired social interaction mitigated the negative effects of tail amputation on cell proliferation in the forebrain but not the midbrain. Social interaction either before or after tail amputation reduced the effect of tail injury, and continuous interaction both before and after caused an even greater buffering effect. Social interaction buffered the proliferation response after short‐term (1 d) or long‐term recovery (7 d) from tail amputation. This is the first report of social buffering of brain cell proliferation in any non‐mammal. Despite the positive association between social stimuli and brain cell proliferation, we found no evidence that fish affiliate more closely following tail injury.Keywords
Funding Information
- Dana Foundation (Research Professor Award)
This publication has 33 references indexed in Scilit:
- Simulated predator stimuli reduce brain cell proliferation in two electric fish species, Brachyhypopomus gauderio and Apteronotus leptorhynchusJournal of Experimental Biology, 2017
- Mechanisms of social buffering of fear in zebrafishScientific Reports, 2017
- Fish Neurogenesis in Context: Assessing Environmental Influences on Brain Plasticity within a Highly Labile Physiology and MorphologyBrain, Behavior and Evolution, 2016
- Predators inhibit brain cell proliferation in natural populations of electric fish, Brachyhypopomus occidentalisProceedings. Biological sciences, 2016
- Influence of long-term social interaction on chirping behavior, steroid levels and neurogenesis in weakly electric fishJournal of Experimental Biology, 2013
- Environmental complexity, seasonality and brain cell proliferation in a weakly electric fish, Brachyhypopomus gauderioJournal of Experimental Biology, 2011
- Presence of conspecifics and their odor-impregnated objects reverse stress-decreased neurogenesis in mouse dentate gyrusJournal of Neurochemistry, 2010
- Electrocommunication signals alone are sufficient to increase neurogenesis in the brain of adult electric fish, Apteronotus leptorhynchusDevelopmental Neurobiology, 2008
- Social interaction and cortisol treatment increase cell addition and radial glia fiber density in the diencephalic periventricular zone of adult electric fish, Apteronotus leptorhynchusHormones and Behavior, 2006
- Sex differences in cell proliferation, cell death and defensive behavior following acute predator odor stress in adult ratsBrain Research, 2003