Effect of Phyllanthus buxifolius Leaf as a Feed Supplement on Liver Function and Haematological Response of Quail (Coturnix coturnix japonica) Challenged with Infectious Newcastle Disease Virus
- 15 August 2017
- journal article
- Published by Science Alert in International Journal of Poultry Science
- Vol. 16 (9), 354-363
- https://doi.org/10.3923/ijps.2017.354.363
Abstract
Background and Objective: Quail breeders are continuously facing high mortality rates due to Newcastle disease virus infection. Administration of 4-6% Phyllanthus buxifolius leaf powder in the diet can decrease fat and cholesterol levels in egg yolk and increase the immunity of unchallenged quail against Newcastle disease virus. This study examines the effects of P. buxifolius leaf powder on liver function and the haematological responses of quail challenged with Newcastle disease virus. Materials and Methods: One day old quail were acclimatized for 14 days in collective bamboo cages. Seventy-five female quail with similar weights were transferred to individual cages and randomized into five groups, each group being fed a commercial diet containing either 0, 2, 4, 6 and 8% P. buxifolius leaf powder. At the age of 47 days, all quail were infected with velogenic Newcastle disease virus. Haemogglutination inhibition tests were conducted on quail at the ages of 45, 65 and 80 days. Liver function tests and white blood cell and platelet counts were evaluated on quail at the ages of 45 and 75 days. Results: Supplementation with P. buxifolius leaf powder significantly increased antibody titers in 75 and 90 days old quail, significantly decreased aspartate amino transferase and alanine amino transferase levels and decreased total leucocyte, thrombocyte, lymphocyte and monocyte counts. Leaf powders of P. buxifolius have a high potential to protect poultry from infection with Newcastle disease virus and reduce spread of the disease. Conclusion: Dietary supplementation with 4-6% P. buxifolius leaf powder does not cause liver damage or inflammation in quail and may protect against infection.Keywords
This publication has 10 references indexed in Scilit:
- Egg Cholesterol and Immunity of Quail (Coturnix coturnix japonica) Diet Phillanthus buxifolius Leaves as Feed SupplementAsian Journal of Agricultural Research, 2016
- Hematological effects of Ipomoea batatas (camote) and Phyllanthus niruri (sampa-sampalukan) from Philippines in the ICR mice (Mus musculus)Asian Pacific Journal of Tropical Biomedicine, 2015
- Insight into Alternative Approaches for Control of Avian Influenza in Poultry, with Emphasis on Highly Pathogenic H5N1Viruses, 2012
- Nudged out of the nicheNature Reviews Immunology, 2011
- Hypoglycemic and hypocholesterolemic activities of the aqueous leaf and seed extract of Phyllanthus amarus in miceFitoterapia, 2006
- Some clinico-pathological changes associated with the aqueous extract of the leaves ofPhyllanthus amarus in ratsPhytotherapy Research, 2005
- Evaluation of Different Programs of Newcastle Disease Vaccination in Japanese Quail (Coturnix coturnix japonica)International Journal of Poultry Science, 2004
- Toxicity of cypermethrin in Labeo rohita fingerlings: biochemical, enzymatic and haematological consequencesComparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 2003
- Normal Hematologic and Serum Biochemical Reference Intervals for Juvenile Wild TurkeysJournal of Wildlife Diseases, 2000
- Antiviral Tannins from Two Phyllanthus SpeciesPlanta Medica, 1999