The global economic crisis, which is linked to the coronavirus pandemic, has also affected pharmaceutical logistics. Therefore, the improvement of logistics processes within the pharmaceutical supply chain to increase the access to health care to the population in a pandemic becomes especially important. The aim of the work is to study and summarize the main problems of pharmaceutical logistics in a coronavirus pandemic and substantiate the reserves to improve the functioning of pharmaceutical supply chains. To achieve the goal of the study, an analysis of the domestic scientific literature and the current regulatory framework of Ukraine was conducted. It has used abstract-logical, monographic research methods and system analysis, as well as the method of expert survey. Realizing the importance of providing the population with necessary medicines during the pandemic in Ukraine on October 14, 2020, the Law «Changes to the article 19 of the Law of Ukraine "On Medicinal Products" on Electronic Retail Trade in Medicines» of September 17, 2020 № 904-IX has enforced. It has been evaluated the factors influencing the efficiency and coordination of the activities of pharmaceutical supply chain participants. A risk management algorithm for pharmaceutical supply chains has been developed, its structural elements and relationships have been identified. The presented algorithm will allow analyzing and estimating any deviations from the planned parameters in pharmaceutical supply chains on the basis of establishment of system of the corresponding indicators and on the basis of this information to define effective methods to counter the risks. The urgency of the problem of increasing the reliability and safety of domestic pharmaceutical supply chains in a pandemic has proved. It is justified that the introduction of digital technologies will increase the reliability, transparency and quality of business processes in the pharmaceutical supply chains during a pandemic, drastic changes in the pharmaceutical market and low predictability of demand for medicines and medical devices. The main problems of logistics in a pandemic in the domestic pharmaceutical industry are studied. It has established that the narrowest places in the organization of pharmaceutical supply chains are the improper organization of information exchange between pharmaceutical supply chain participants and the insufficient professional level of production interaction of managers. It has established the priority directions of increase of stability and reliability of functioning of pharmaceutical supply chains which is a necessary condition of accessibility of pharmaceutical provision of the population, especially in the conditions of a pandemic.