Abstract
Nonpharmaceutical interventions (NPIs) mitigate COVID-19. Essential workplaces remained open during COVID-19, but few U.S.-based settings detail outcomes. Mercury Systems is a U.S.-based manufacturing company that remained open during COVID-19. NPIs – distancing, masking, hand hygiene, ventilation- were successively deployed from March-August 2020. The company expanded sick leave, asked employees to report work outages from illness, and administered employee satisfaction surveys. Three sites in Arizona, southern California and New Hampshire administered testing campaigns via RT-PCR of nasal swabs in late July-early August for all employees at work or at home self-isolating due to symptoms. Descriptive statistics summarized findings. Among 586 employees at three sites, only 1.5% employees developed severe illness over the study duration. Testing campaigns revealed 44 with positive PCR results at a cycle threshold (CT) <37 (likely infectious) and 61 with a CT≥37 (low-level viral load). True positivity rates were consistent with community prevalence at the time: 1.1% in New Hampshire, 6.2% in California, 12.9% in Arizona. Of all employees with positive tests, 99% were asymptomatic. Employee surveys showed high satisfaction. In a multi-site U.S. company which instituted NPIs for COVID-19 mitigation, the proportion of asymptomatic COVID-19 infections on surveillance testing was high (99%). Although surges in community transmission were seen in two sites over the study, employee prevalence reflected community prevalence, despite daily workplace presence. This study demonstrates that NPIs likely mitigate severe COVID-19 illness, that PCR tests should incorporate CT values, and that expanded sick leave likely encourages self-isolation, suggesting strategies for work re-openings.
Funding Information
  • National Institute of Allergy and Infectious Diseases
  • National Institutes of Health (R01AI158013)