In natural leather production polymeric compounds are generally used during leather finishing coating. However, given that liquid processing is crucial for derma structure and properties development, we have identified the rationale for applying polymers based on maleic and acrylic acids during chrome and titanium tanning of garment leather by analysing specimens of polymer-mineral tanning. We have applied analysis techniques traditional for leather industry (strength of surface, strength and percentage extension, shrinkage temperature, moisture content, mineral substances content etc.), as well as mathematical statistics techniques, in order to do it. It has been established that structure and custom properties development of polymer-mineral tanning leather products has been improved as compared with pickle-chrome tanning ones.