COVID-19 has been a dreadful experience for the entire globe. Though the world has again picked up the pace in terms of socializing and economic growth, the overall health condition of the substantial population around the globe has deteriorated drastically and is on a continual decline. Symptoms including Fatigue, Headache, sleep disorders, anxiety, loss of taste, lung problems- dyspnea, cough, persistent oxygen requirement, palpitation chest pain, kidney disorder, hair loss, depression, etc. have been observed as post COVID syndromes in the COVID affected patients. This review article discusses the persistent symptoms, long-term complications, future challenges, and preventive measures of the COVID affected people.