A virus is an ultramicroscopic (20-300 nanometers in diameter) metabolically inert, infectious agent that replicates only within the cells of living hosts. Coronavirus disease 2019 (COVID-19) is a viral infectious disease caused by SARS-CoV-2 and is announced by World Health Organization (WHO) as a pandemic. As of 23 August 2020, 23,407,334 infected people and 810,242 deaths were reported worldwide. COVID-19 has affected our daily lives and influences all aspects of life, including economic, social, health, etc. On the healthcare level, the world is faced with many challenges, including diagnosis, quarantine, and treatment of suspected cases, overloaded doctors and healthcare professionals and the requirement of a high level of protection. This research focused on preventive measures - preventive medicine - to combat coronavirus according to Islamic law's and modern medicine's perspective. Sharia focuses on preserving diseases to achieve its objectives thereby, so it has legislated some of the rulings that achieve this purpose, so it based its provisions on bringing interests and warding off evil. This research has been divided into two requirements; the first requirement is that the researcher talked about preventive strategies, one of the most important branches of medicine because it precedes disease before it occurs to be rectified with awareness and guidance. The second requirement: supporting scientific research to make vaccines and medicines is the most important findings of the researcher. Besides the review intent to explaining the extent of compatibility and difference between practical applications in Islamic jurisprudence and modern medicine, Explaining the importance of treatment from diseases and epidemics and the necessity of supporting scientific research to find medicines and vaccines( not only preventive strategies), and A statement of the importance and necessity of adhering to the instructions and instructions issued by the competent medical authorities and institutions with expertise and competence to prevent transmission of infection by prevention, treatment and taking vaccinations.