Retinoblastoma – Typical and atypical clinical manifestations presented at tertiary eye care centre
Open Access
- 15 December 2022
- journal article
- Published by IP Innovative Publication Pvt Ltd in Indian Journal of Clinical and Experimental Ophthalmology
- Vol. 8 (4), 543-548
- https://doi.org/10.18231/j.ijceo.2022.110
Abstract
: Purpose is to study the various typical and atypical manifestations of the retinoblastoma presented to our department.: Prospective study.: 2 years, January 2020 to December 2021.: All children presented with various signs and symptoms and cases with tumour suspicious manifestations were evaluated. Detailed birth history from parents, slit lamp examination, indirect ophthalmoscopy, B Scan, CT Scan Orbit (plain and contrast), MRI Orbit (plain and contrast) when tumour extension was suspected and documentation done in all cases.: Atypical manifestations requires proper evaluation to exclude Pseudo retinoblastomas. Many clinical conditions will masquerade the tumour and cause confusion in diagnosis. Pseudo retinoblastomas which reported in our study were commonly PHPV and Coats disease. One case of Retinoblastoma was also presented like Ocular cysticercosis with inflammatory signs in anterior and posterior segment, oral steroids were given, vitreous seeds which were present in anterior chamber disappeared after steroids and fundus showed creamish white lesion filling the entire vitreous cavity. Masquerades will cause delay in the diagnosis, which can lead to extension of tumour.: Diagnosis is not easy, most of the times in children particularly when media is not clear, delay in diagnosis may require enucleation where globe salvage may not be possible, sometimes intracranial extension of the tumour will increase the mortality.Keywords
This publication has 12 references indexed in Scilit:
- Retinoblastoma in Children Older than 6 Years of AgeOcular Oncology and Pathology, 2020
- Recurrent retinoblastoma with intracranial extension post enucleationIP Journal of Nutrition, Metabolism and Health Science, 2020
- Modern treatment of retinoblastoma: A 2020 reviewIndian Journal of Ophthalmology, 2020
- Diffuse anterior retinoblastoma: current conceptsOncoTargets and Therapy, 2015
- Retinoblastoma in a 12 year old girl: a case reportInternational Journal of Medical Research & Health Sciences, 2014
- Diffuse infiltrating retinoblastoma coexisting with ocular toxoplasmosisInternational Ophthalmology, 2013
- Current therapy and recent advances in the management of retinoblastomaIndian Journal of Medical and Paediatric Oncology, 2012
- MRI of retinoblastomaThe British Journal of Radiology, 2011
- Bilateral Retinoblastoma: A Dominantly Inherited AffectionBMJ, 1972
- Diffuse infiltrating retinoblastoma.British Journal of Ophthalmology, 1971