Diet and Kidney Disease in High-Risk Individuals With Type 2 Diabetes Mellitus

Abstract

In industrialized countries, as life expectancy increases and populations increase in age, type 2 diabetes mellitus and associated chronic kidney disease (CKD) have become major public health problems. Glycemic control, antihypertensive therapy, and inhibition of the renin-angiotensin system are known to affect established diabetic renal disease. However, little is known about the long-term effect of diet on the incidence and progression of early-stage diabetic CKD. The slow progression of CKD, the competing risk of death among individuals with diabetes and CKD, and the difficulty in assessing dietary intake contribute to this lack of information.