Glycemic control among children with type 1 diabetes mellitus and its determinants in a resource-limited setting
- 20 April 2022
- journal article
- research article
- Published by Walter de Gruyter GmbH in Journal of Pediatric Endocrinology and Metabolism
- Vol. 35 (6), 813-817
- https://doi.org/10.1515/jpem-2022-0144
Abstract
Objectives Glycemic control is an important parameter that can predict long-term complications of diabetes mellitus. It can be affected by many factors. Hence, identifying those factors for improving disease outcomes is essential. The purpose of this study was to assess glycemic control in children who were treated with a conventional insulin regimen and to identify its associated factors. Methods A retrospective cohort study was conducted among children with type one diabetes mellitus (T1DM) who had follow-up from November 2015 to November 2020 at the pediatric endocrinology clinic of St. Paul’s Hospital Millennium Medical College in Addis Ababa, Ethiopia. Glycemic control was assessed by measuring glycosylated hemoglobin (HbA1C) and children who had HbA1C within three to six months of the data collection were recruited. Results A total of 106 children with TIDM who were on conventional insulin therapy were included in this study. Their median age at diagnosis was nine years, 47.2% were females, and 57.5% were from urban areas. The average HbA1c of the children was 9.7%. The majority (85.2%) of the children had poor glycemic control (>7.5%). Younger age, longer disease duration, and urban residence were found to be significant predictors of good glycemic control. Conclusions A significant majority of children with T1DM had poor glycemic control. This calls for the need to create access to intensive diabetes care by health authorities and stakeholders to prevent the long-term complications of T1DM.Keywords
This publication has 27 references indexed in Scilit:
- Predictors of glycemic control in children with Type 1 diabetes mellitus in Assiut-EgyptIndian Journal of Endocrinology and Metabolism, 2012
- Glycemic Control in Pediatric Type 1 Diabetes: Role of Caregiver LiteracyPEDIATRICS, 2010
- Association Between Adherence and Glycemic Control in Pediatric Type 1 Diabetes: A Meta-analysisPEDIATRICS, 2009
- Glycemic Control in Youth with Diabetes: The SEARCH for Diabetes in Youth StudyThe Journal of Pediatrics, 2009
- Assessment of risk factors of poor metabolic control in type 1 diabetic children assisted in a public hospital in ArgentinaPediatric Diabetes, 2008
- Factors influencing glycaemic control in children with Type 1 diabetesDiabetic Medicine, 2008
- Improved Glycemic Control in Poorly Controlled Patients with Type 1 Diabetes Using Real-Time Continuous Glucose MonitoringDiabetes Care, 2006
- The role of socioeconomic status, depression, quality of life, and glycemic control in type 1 diabetes mellitusThe Journal of Pediatrics, 2006
- Beneficial effects of intensive therapy of diabetes during adolescence: Outcomes after the conclusion of the Diabetes Control and Complications Trial (DCCT)The Journal of Pediatrics, 2001
- Factors Associated With Glycemic Control: A cross-sectional nationwide study in 2,579 French children with type 1 diabetesDiabetes Care, 1998