Use of Breath Analysis for Diagnosing COVID-19: Opportunities, Challenges, and Considerations for Future Pandemic Responses

Abstract

Due to the COVID-19 pandemic, there is currently a need for accurate, rapid, and easy-to-administer diagnostic tools to help communities manage local outbreaks and assess the spread of disease. The use of Artificial Intelligence within the domain of breath analysis techniques has shown to have potential in diagnosing a variety of diseases such as cancer and lung disease by analyzing volatile organic compounds (VOCs) in exhaled breath. This combined with their rapid, easy-to-use, and non-invasive nature makes them a good candidate for use in diagnosing COVID-19 in large scale public health operations. However, there remains issues with their implementation when it comes to the infrastructure currently available to support their use on a broad scale. This includes issues of standardization, and whether or not a characteristic VOC pattern can be identified for COVID-19. Despite these difficulties, breathalysers offer potential to assist in pandemic responses and their use should be investigated.