Current cellular architecture will not be suitable for 5G because it will not scale to the anticipated number of connected endpoints and their rich diversity. The distribution of the previously centralized Core Network (CN) functionality, e.g., Access Authentication and Authorization, has to be decentralized, leading to the demise of the most utilized tool of network security engineering, Physical Security Perimeter. The asserted and attested Platform Integrity of the network nodes that comprise the edges of the network, the network cloud, “network fog”, and the endpoints will allow mobile network operators (MNOs) to create Virtual Network Perimeters and allow highly reliable, diverse, and flexible 5G networks. This article describes the reasons for such network transformation, provides references to applicable standardization activities, and uses the examples of support for Unmanned Aerial Vehicles (UAV) and connected automobiles by 5G networks to justify the need for Platform Integrity.