Glaucoma is a progressive optic neuropathy often associated with increased intraocular pressure (IOP; normal range 8-22 mm Hg), which is the only disease-related effect that can be modified. Treatment of open-angle glaucoma in adults is reviewed here. Topical drugs are listed in the Table; laser trabeculoplasty and surgery are alternatives to medication. The complete article can be found in the December 2, 2019, issue of The Medical Letter on Drugs and Therapeutics.