Research Progress in the Relationship between Connexin 43 and the Occurrence and Development of Breast Cancer
- 1 January 2022
- journal article
- Published by Hans Publishers in World Journal of Cancer Research
- Vol. 12 (02), 81-89
- https://doi.org/10.12677/wjcr.2022.122011
Abstract
Breast cancer occupies the first place in the occurrence of female malignant tumors. Connexin 43 (Cx43) has abnormal expression in breast cancer, and plays a role in the occurrence and development of breast cancer. This article mainly discusses the research progress of Cx43 in breast cancer, and discusses its expression in normal breast tissue, primary breast cancer and distant metastasis, so as to provide new ideas for the treatment of breast cancer.Keywords
This publication has 43 references indexed in Scilit:
- Estrogen receptor signaling as a target for novel breast cancer therapeuticsBiochemical Pharmacology, 2013
- The potential prognostic value of connexin 26 and 46 expression in neoadjuvant-treated breast cancerBMC Cancer, 2013
- The severity of mammary gland developmental defects is linked to the overall functional status of Cx43 as revealed by genetically modified miceBiochemical Journal, 2012
- The effect of the PQ1 anti-breast cancer agent on normal tissuesAnti-Cancer Drugs, 2012
- Partial Mesenchymal to Epithelial Reverting Transition in Breast and Prostate Cancer MetastasesCancer Microenvironment, 2011
- Connexin-43 upregulation in micrometastases and tumor vasculature and its role in tumor cell attachment to pulmonary endotheliumBMC Medicine, 2008
- Decreased levels of connexin43 result in impaired development of the mammary gland in a mouse model of oculodentodigital dysplasiaDevelopmental Biology, 2008
- Transcriptome analysis reveals an osteoblast-like phenotype for human osteotropic breast cancer cellsBreast Cancer Research and Treatment, 2006
- Developmental expression patterns and regulation of connexins in the mouse mammary gland: expression of connexin30 in lactogenesisCell and tissue research, 2004
- Analysis of Multiple Gap Junction Gene Products in the Rodent and Human Mammary GlandExperimental Cell Research, 1995