Modulation of Gas-Phase Lithium Cation Basicities by Microsolvation
- 9 September 2019
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Society for Mass Spectrometry
- Vol. 30 (10), 1857-1866
- https://doi.org/10.1007/s13361-019-02312-5
Abstract
In contrast to the extensive knowledge of lithium cation affinities and basicities, the thermochemistry of microsolvated lithium cations is much less explored. Here, we determine the relative stabilities of Li(A,B)n+ complexes, n = 2 and 3, by monitoring their gas-phase reactions with A and B substrate molecules, A/B = Me2O, Et2O, tetrahydrofuran, and MeCN, in a three-dimensional quadrupole-ion trap mass spectrometer. Kinetic analysis of the observed ligand displacement reactions affords equilibrium constants, which are then converted into Gibbs reaction energies. In addition, we use high-level quantum chemical calculations to predict the structures and sequential ligand dissociation energies of the homoleptic Li(A)n+ complexes, n = 1–3. As expected, the ligands dissociate more easily from complexes in higher coordination states. However, the very nature of the ligand also matters. Ligands with different steric demands can, thus, invert their relative Li+ affinities depending on the coordination state of the metal center. This finding shows that microsolvation of Li+ can result in specific effects, which are not recognized if the analysis takes into account only simple lithium cation affinities and basicities.Keywords
Funding Information
- Deutsche Forschungsgemeinschaft (389479699/GRK2455)
This publication has 55 references indexed in Scilit:
- Mechanisms of Nucleophilic Organocopper(I) ReactionsChemical Reviews, 2011
- Association and Dissociation of Lithium Cyanocuprates in Ethereal SolventsOrganometallics, 2011
- A consistent and accurate ab initio parametrization of density functional dispersion correction (DFT-D) for the 94 elements H-PuThe Journal of Chemical Physics, 2010
- Aggregation and Reactivity of Organozincate Anions Probed by Electrospray Mass SpectrometryOrganometallics, 2008
- The Lithium Cation Binding Energies of Gaseous Amino AcidsThe Journal of Physical Chemistry A, 2003
- Efficient use of the correlation consistent basis sets in resolution of the identity MP2 calculationsThe Journal of Chemical Physics, 2002
- Toward reliable density functional methods without adjustable parameters: The PBE0 modelThe Journal of Chemical Physics, 1999
- Cation−Ether Complexes in the Gas Phase: Bond Dissociation Energies and Equilibrium Structures of Li+[O(CH3)2]x, x = 1−4The Journal of Physical Chemistry, 1996
- Binding of lithium(1+) ion to Lewis bases in the gas phase. Reversals in methyl substituent effects for different reference acidsJournal of the American Chemical Society, 1978
- Note on an Approximation Treatment for Many-Electron SystemsPhysical Review B, 1934