Microwave assisted synthesize of new some benzimidazole derivatives and determination of protonation constant of these compounds in non-aqueous media
Open Access
- 31 March 2013
- journal article
- Published by European Journal of Chemistry in European Journal of Chemistry
- Vol. 4 (1), 25-28
- https://doi.org/10.5155/eurjchem.4.1.25-28.729
Abstract
A series of 2-substituted benzimidazole derivatives have been synthesized via microwave mediated process. Different benzimidazole derivatives were titrated with tetrabutylammonium hydroxide in four non-aqueous solvents (isopropyl alcohol, N,N-dimethylformamide,tert-butyl alcohol and acetonitrile), using potentiometric method. The half neutralization potential values and the corresponding pKa values were determined for all cases.Keywords
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